New-Onset Diabetes, Antihypertensive Treatment, and Outcome
نویسندگان
چکیده
منابع مشابه
New-onset diabetes, antihypertensive treatment, and outcome.
New-onset diabetes (NOD) confers increased risk for cardiovascular disease and all-cause mortality in different clinical settings.1,2 In the specific context of hypertensive subjects exposed to the long-term effects of antihypertensive drugs, a study from our group3 and a recent 28-year follow-up study from Sweden4 showed a greater risk of major cardiovascular disease in hypertensive subjects w...
متن کاملNew-onset diabetes and antihypertensive treatment
INTRODUCTION Chronic diseases substantially contribute to the continuous increase in health care expenditures, including type-2 diabetes mellitus as one of the most expensive chronic diseases. Arterial hypertension presents a risk factor for the development of type-2 diabetes mellitus. Numerous analyses have demonstrated that antihypertensive therapies promote the development of type-2-diabetes...
متن کاملAntihypertensive therapy, new-onset diabetes, and cardiovascular disease
Type 2 diabetes mellitus is a worldwide epidemic with considerable health and economic consequences. Diabetes is an important risk factor for cardiovascular disease, which is the leading cause of death in diabetic patients, and decreasing the incidence of diabetes may potentially reduce the burden of cardiovascular disease. This article discusses the clinical trial evidence for modalities assoc...
متن کاملAntihypertensive therapy and the risk of new-onset diabetes.
Numerous studies have consistently demonstrated that certain classes of antihypertensive medications have differential effects on carbohydrate and lipid metabolism in humans. In general, higher doses of thiazide diuretics (i.e., 25 mg/day hydrochlorothiazide) and -blockers, at any antihypertensive dose, worsen glycemic control, with -blockers worsening insulin sensitivity (1). Conversely, ACE i...
متن کاملAntihypertensive Drug Use and New-Onset Diabetes in Female Patients with Coronary Artery Disease
Antihypertensives have been linked to new-onset diabetes (NOD) and different classes of antihypertensives may alter the risk for the development of NOD; however, the effect of different antihypertensives on the development of NOD in women with hypertension and coronary artery disease (CAD) has not been well studied. The purpose of this study is to investigate the association between usage of di...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2007
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.107.096966